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Cancer Prevention Research (Phila) 2009;2(4):345352

However, their insufficient sensitivity for early renal injury and the lack of efficient biomarkers contribute to high rates of missed diagnoses (Pillai and Fulmali, 2023)

[DOI] [PMC free article] [PubMed] [Google Scholar] Klammt C

For pancreatic cancer, saikosaponin D could inhibit proliferation and induce apoptosis of BxPC3, PANC1, and Pan02 cells by triggering cleavage of caspase 3 and caspase 9 and increasing expression of FoxO3a via activating the mitogen-activated protein kinase kinase 4-c-Jun N-terminal kinase (MKK4-JNK) pathway [266]

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