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Results Endogenous MOTS-c levels increase upon exercise in humans To determine if endogenous MOTS-c responds to physical exertion, and thus may be involved in driving adaptation to enhance physical capacity, we collected skeletal muscle and plasma from sedentary healthy young male volunteers (24.5 3.7 years old and BMI 24.1 2.1) that exercised on a stationary bicycle (Fig

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GHK initiates the cellular downstream pathway and exerts bioactivities through binding with cell surface receptors ( In vitro and in vivo studies proved that this combination stimulates the synthesis of collagen and glycosaminoglycans (Figure 1), respectively