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Understanding how targeted fat loss affects lipid metabolism could inform the development of interventions for dyslipidemia and atherosclerosis prevention

Pathogenesis of alcohol-induced liver disease: classical concepts and recent advances

doi: 10.1038/s41467-021-23902-6 66 LiJ-YFengY-HLiY-XHeP-YZhouQ-YTianY-Pet al

In rodent models of alcohol use disorder (AUD), NAC given in acute doses or repeatedly (during abstinence period) reduced alcohol intake [26,27,28], and was responsible for the development of alcohol sensitization [29], extinction responding [30], alcohol relapse [27, 28, 31], alcohol withdrawal-induced anxiety and depression [32, 33] (Table 1)