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Risk factors for B12 deficiency Without saliva, B12 will not bind to the salivas R-protein, and the bodys ability to absorb it is inhibited
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Full piece, with the regulatory and immunogenicity detail, in the link in comments
Low levels of stomach acid, medications, excessive alcohol consumption, and other issues like surgeries and health conditions can all contribute to a diminished ability to absorb the needed amounts of B12
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Ley EC, Morishita TY, Harr BS, Mohan R , Brisker T
