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Because B12 is naturally found only in animal-based ingredients, plant-based diets must include synthetic supplementation to meet a dogs nutritional needs

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Vitamin B(12) deficiency associated with concomitant metformin and proton pump inhibitor use

189,190 The idea that a site-specific DNA binding protein might regulate transcription of resistance genes by reversible binding of a metal first emerged by identifying potential metal binding sites in these DNA binding proteins

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