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Li X, Huai Q, Zhu C, Zhang X, Xu W, Dai H, et al

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The 24-h toxicity decreased with increasing pH in the same manner as the 48-h toxicity (Table 1)

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By contrast, serine itself is an allosteric inhibitor of PHGDH, and this allosteric inhibition can spontaneously disappear at low serine levels (Sugimoto and Pizer, 1968)

You don't need to label every bend and fitting because the drawing is to scale
