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This is a hypothetical example of a positive feedback loop, i.e., increased mitochondrial OxS promotes increased glycemia, promoting increased glycationinactivation of GPX enzymes with a further increase in skeletal muscle mitochondrial OxS and glycemia

10.1016/S0021-9258(19)44055-6 [DOI] [PubMed] [Google Scholar] Francis MJ, Jones EE, Levy ER, Martin RL, Ponnambalam S, & Monaco AP (1999)

Moreover, the content of VOCs increased with the rise in ethylene production

[DOI] [Google Scholar] 27.Misra A.L., Yeh S.H., Woods L.A

Eukaryot Cell 4: 392400 WaypaGB,MarksJD,GuzyR,MungaiPT,SchriewerJ,DokicD,SchumackerPT (2010) Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells

The patient did not have any neurological symptoms