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[DOI] [PubMed] [Google Scholar] 49.Panday A., Sahoo M.K., Osorio D., Batra S

Subjects will be told to take the first dose of study medication after breakfast each day and the second dose in the evening after dinner

ConcentrationAdverse Reaction Relationships There is a relationship between increasing codeine plasma concentration and increasing frequency of dose-related opioid adverse reactions such as nausea, vomiting, CNS effects, and respiratory depression

& Trapani, J

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