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Description
This isn't unusual for novel research compounds

Grouping: Young control group, elderly control group, AOD 9604 group (500 g/kg/day), positive drug group (alendronate sodium, 10mg/kg/week)
This ensures immediate bioavailability, especially for patients with absorption issues such as gut inflammation, low stomach acid, or conditions like pernicious anemia

Promote renal calcium reabsorption Renal tubular calcium transport: upregulate the expression of renal tubular calcium channel (TRPV5), reduce urinary calcium excretion by 30% -40%, increase blood calcium concentration, and increase bone calcium deposition Evidence from preclinical studies on AOD 9604 bone protection (animal experiments) Postmenopausal osteoporosis (OVX rat model) Experimental Design: Animal: 6-month-old female SD rats underwent bilateral ovariectomy (OVX) to establish a postmenopausal osteoporosis model

Maternal vitamin D supplementation during pregnancy

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