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GSSG and residues that compose the substrate-binding site are shown as sticks

Jumanji Domain-Containing Protein 3 (JMJD3), a key histone demethylase, plays an essential role in regulating gene expression by removing the H3K27me3 mark

If you just a have a drink or 2 over the course of a couple hours, your liver probably has enough glutathione to handle the acetaldehydes

Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence

One of these mechanisms is through the activation of transcription factors, such as nuclear factor erythroid 2 (NRF2), which promotes the expression of genes involved in oxidative stress response

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