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The 660-nm light irradiation was conducted at 12 h post injection (5 mW cm 2 , 1 h)

Lactate-dependent regulation of immune responses by dendritic cells and macrophages
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Across multiple independent cohorts (Table 1), UC is consistently associated with increased relative abundance of Proteobacteriaparticularly the Enterobacteriaceae alongside reduced levels of health-associated groups such as Bifidobacterium , Lachnospiraceae, and Verrucomicrobia (e.g., Akkermansia
