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At the same time, Rac GTPases play an important role in dendritic cell migration, as Rac1/2 deficient dendritic cells are not able to efficiently reach lymph nodes 79
Therefore, more in-depth studies are needed to elucidate the different effects of NADPH on ROS generation and other pathways involved in high glucose-induced ROS generation

Cells were lysed at 4 C in a radioimmunoprecipitation assay (RIPA) lysis buffer (Beyotime Biotechnology)

[DOI] [PubMed] [Google Scholar] 56.Kato T., Ito Y., Hosono K

Am J Physiol Cell Physiol 320(2):C182c194

elegans life span (Morcos et al., 2008)
