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Acquired (Secondary)- an iron-loading anemia, such as thalassemia or sideroblastic anemia, in which erythropoiesis is increased but ineffective causes excessive iron deposition in parenchymal tissues and end organ failure

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Hepatology 14(1):1015 Duthie SJ, Grant MH (1989) The toxicity of menadione and mitozantrone in human liver-derived Hep G2 hepatoma cells

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