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[DOI] [PMC free article] [PubMed] [Google Scholar] [101].Wang XD, Vatamaniuk MZ, Wang SK, Roneker CA, Simmons RA, Lei XG, Molecular mechanisms for hyperinsulinaemia induced by overproduction of selenium-dependent glutathione peroxidase-1 in mice

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In pernicious anaemia, the immune system mistakenly attacks the gastric parietal cells that produce intrinsic factor, leading to B12 deficiency over time

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However, in some extreme cases, this is not enough, and human skin cells require additional external protection

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N-acetylcysteine (NAC) Dietary Modifications: Eating a diet rich in foods that naturally boost glutathione levels or contain precursors to glutathione synthesis might be recommended

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Pharmacol Res 156:104806

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Furthermore, most available studies are of short duration and lack long-term follow-up to assess whether repeated or chronic IF leads to sustained alterations in thyroid function or clinically meaningful hypothyroidism [60] (Table 2)

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