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PAI-1, Plasminogen Activator Inhibitor-1

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The significant reduction in oxygen uptake and the tendency to achieve lower blood lactate concentrations at the final ergometric load (VO2peak) during fasting observed in our study are also likely related to lower maximum power output and shorter exercise test duration

This finding argues that the differences in activity between the two compounds results from mechanistic differences caused by inhibition of their respective targets

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