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In a large study of over 18,000 patients, rates of gastrointestinal side effects were similar between tirzepatide and semaglutide users, with no significant difference between the drugs
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[PubMed] 3
In a weight loss clinic for Semaglutide in Los Angeles trial, when Wegovy was administered in conjunction with diet and exercise, participants lost an average of 5-20% of their body weight over 68 weeks [4]
This represents clinically significant improvement associated with reduced cardiovascular risk, improved glycemic control in those with diabetes, and decreased joint stress
