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A brief illustration of these mechanisms is shown in Figure 2 and described in detail below

Synergy effects can enhance the therapeutic efficacy of ACDs, but may also lead to adverse toxicity and complicate dosing regimens

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Still, it can also prove a challenge, as many factors can cause a drop in appropriate levels, such as poor nutrition, environmental toxins, stress, and aging

However, it may interact with adaptive immunity through reduction of immunoglobulin secretion from plasma cells and production of pro-inflammatory cytokines, which alter the function of T cells (Figure 3)

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