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These reactions create an ATP-depleting futile 5-oxoproline cycle that consumes two ATP molecules for each circuit

Conversely, Car4 OE cells showed significantly reduced ROS production (Fig

doi: 10.5114/ceji.2019.87498 74 PrasadCDasguptaDTripathiASteeleNPyaramKSundarIKet al
GPX4 and FSP1 use GSH and ubiquinol, respectively, to detoxify lipid hydroperoxides to lipid alcohols (61)

doi: 10.3390/foods13203312
