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The copper(II)-GHK binding chemistry is mapped in detail (Lau & Sarkar)

In the presence of free ions of metals with a higher binding affinity, such as Cd 2+ or Hg 2+ , or of metal ions in conjugate forms, such as the glutathione-Cu(I) [148] and the glutathione-Cd [149] conjugates, these metals bind MT thiol groups and the bound Zn(II) is released [150]

J Neurobiol