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Mechanism of Action Bind to H/K ATPase on parietal cell canalicular membrane Irreversible inhibition prolonged acid suppression Effect lasts 2448 hours despite short plasma half-life Common PPIs Omeprazole Esomeprazole Pantoprazole Lansoprazole Rabeprazole Dexlansoprazole Indications / Uses Gastrointestinal Disorders Gastroesophageal reflux disease (GERD) Peptic ulcer disease (gastric & duodenal) NSAID-induced ulcers Zollinger-Ellison syndrome H

Cranial nerve palsies are generally not life-threatening and are often temporary, though they may be painful at first

Methionine helps break down fats and supports detoxification processes within the liver