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Minimal Dead Space: Most modern insulin syringes are designed with a plunger that extends into the needle hub, displacing nearly all the fluid

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Glucose uptake and entry into the cell - Activation of the insulin receptor promotes glucose transport into the cell via the GLUT4 transporter

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Others are conceptual misunderstandings that lead to weeks of incorrect dosing before anyone notices

Probably, uh, in my, my guess, and this is just a total guess on my part, yeah