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The oxidative damages of biomolecules specifically of DNA due to the accumulation of hydroperoxides and other ROS ultimately lead to the loss of cell viability or cell death through various death mechanisms like apoptosis, autophagy, necrosis, ferroptosis, and mitotic catastrophe (Fig
Chen YY, Zeng XT, Gong ZC, Zhang MM, Wang KQ, Tang YP, et al
Interestingly, in cells that lack PERK, peroxides such as H 2 O 2 accumulate after ER stress

Available online: 101.Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer

30 , e1801362 (2018)

A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of bioactive peptides