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During the antigen recognition process, ROS are generated which function as second messengers to activate inflammatory signaling networks like MAPK and NF-B, and GSH buffering maintains the conditions to support those pathways (Schieber and Chandel, 2014)

Sommerhoff CP, Nadel JA, Basbaum CB, Caughey GH

Results from the five tGSH studies were harder to interpret given that 40% of these studies did not have a clear separation of age groups
