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43 (Mar), 110 (2018)

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This could result in potentially life-threatening opioid intoxication (respiratory compromise or arrest, circulatory collapse, etc.) if the patient uses previously tolerated doses of opioids

This is the Phase 3 dose typically reached during weeks 9 through 12 of the standard escalation protocol

2025 [cited 3rd June 2025] CDSCO [Internet]
