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Inhibiting glutaminase may increase the susceptibility of KEAP1 mutant tumors to immunotherapy.57 In addition, Baird and Yamamoto found that NRF2-activated cells were significantly immunoedited, allowing the cancer cells to evade immune screening and promote the progression of malignant neoplasms

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doi: 10.3389/fnmol.2023.1219574 40

The association of systemic oxidative stress with insulin resistance: mechanistic insights from studies in Bartters and Gitelmans syndromes
