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For data-dependent scanning mode, MS/MS normalized collision energy was set to 20, activation Q 0.25, activation time 25 ms, with a 1 m /z isolation window, while a reject mass list was generated by injecting blank samples consisting in a mixture of acetonitrile:water:formic acid (50:49.9:0.1, v/v/v)

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It biodegrades through hydrolysis and is excreted via respiration, urine or microphage (blood cell) activity

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