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They revealed a shift in redox potential in the longitudinal zones of root tips (Jiang et al
Subsequent studies found that HIFs can also activate glycolytic enzymes to promote a glycolytic switch from oxidative phosphorylation to glycolysis 23 such as in cancer cells (Warburg effect) or during myocardial IR injury 24
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A notable example is naringenin, a hydrophobic flavonoid with limited aqueous solubility and stability
