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The discrepancy between serum presence and tissue-level effects is the single most misunderstood variable in peptide pharmacokinetics

Overall, the developed DRG organoid system represents a valuable platform for modeling and testing therapeutic interventions for FRDA and other pathologies affecting the peripheral nervous system

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Key RTKs in eye include VEGF receptors (VEGFR1, VEGFR2, VEGFR3) regulating angiogenesis, FGF receptors (FGFR1-4) controlling cell proliferation and differentiation, EGF receptor family supporting epithelial cell growth, PDGF receptors modulating pericyte recruitment and vessel stabilization