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The high proline content (4 of 15 residues, including a triple Pro-Pro-Pro stretch at positions 3 to 5) gives BPC-157 unusually good resistance to gastric and intestinal proteases, which is why some published animal work uses oral administration
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[DOI] [PMC free article] [PubMed] [Google Scholar] 766
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10.1038/376768a0 Nature 8 BouattourM.RaymondE.QinS.ChengA
