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In addition, this treatment was associated with side effects, including malaise and cardiac arrhythmias

[DOI] [PubMed] [Google Scholar] 79.Papandreou I, et al

Despite these advances, significant challenges persist in translating these complex biological insights into routine clinical practice (127, 164)

[DOI] [PMC free article] [PubMed] [Google Scholar] Hubbard R., Lewis S., Richards K., Johnston I., Britton J

Most people see improvement within 48 weeks, especially if they were zinc deficient

[71] evaluated the effect of ADMSCs on NP cells in a non-physiological mechanical stimulation environment, and found that ADMSCs prevented NP apoptosis by inhibiting caspase-9 and caspase-3, and promoted the TIMP expression by increasing the amount of ECM, thereby inhibiting the effect of MMPs