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HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain

doi: 10.1016/j.postharvbio.2022.112145 35 LiuH.HeX.MaZ.XuW.LiuM.LiuH
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Cellular antioxidant defense mechanisms The constant formation of prooxidants in the body is balanced by their inactivation by the antioxidant system

Further, in vivo experiments on IL-6 transgenic mice with chronic inflammation revealed similar alterations in the cerebellum, characterized by increased microglial number and activation, pronounced neurodegenerative changes, and significant loss of PCs (Childs et al., 2021)

Adv Sci (Weinh) (2019) 6(21):1901048
