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Similar content being viewed by others Introduction Tyrosinase (TYR) is a crucial and rate-limiting type-3 copper-containing oxidoreductase and mainly participates in two distinct reactions of melanin synthesis 1,2

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1,2 Although the clinical diagnosis of PD relies on the appearance of motor manifestations, extensive neuropathological dissemination initiates decades earlier, posing a significant challenge for early diagnosis

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In the hippocampal region of the brain, there was evidence that rats fed ashwagandha inhibited acute alterations in the expression of proteins involved in synaptic plasticity, cell survival, and death

This system holds promise for effective delivery of therapeutics to treat PD as well as other CNS disorders 126