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Mechanisms Contributing to the Nephrotoxicity of Haloalkene Cysteine S -Conjugates: Toxicant Channeling Haloalkene cysteine S -conjugates are especially toxic to renal mitochondria (e.g., Anders et al., 1988, Chen et al., 2001, Groves et al., 1993, Lash and Anders, 1986)

Neurological functions Several neurological diseases, such as Alzheimers disease and Parkinsons disease, are characterized by disrupted metabolism of the redox-active metals copper and/or iron and/or non-redox zinc (Simunkova et al

Compound-level evidence does not automatically validate the blend

There are no definite causes of mouth ulcers, but some injuries, allergies, or sensitivities may trigger them

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1c) and a fixed effect meta-analysis increased the significance of the observed association ( P = 1.1 10 12 )