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This correlates well with the fact that TyrOH is regulated by the binding of catecholamines, while PheOH is regulated by the substrate binding to an allosteric site (Fitzpatrick, 2015)

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In this study by Ellis [04], chronic users were tested at 20 ng/ml and 100 ng/ml, but not at the normal standard of 50 ng/ml

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However, its worth noting that this study used intravenous deliverynot an oral supplementin a very specific clinical context, so its difficult to generalize these results to everyday use or weight loss