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Eisner MD, Anthonisen N, Coultas D, Kuenzli N, Perez-Padilla R, Postma D, et al

By engaging this master switch, MOTS-c effectively mimics many of the cellular benefits of exercise and caloric restriction, positioning it as a powerful agent for improving systemic metabolic health

Whether this unique pattern worsens the obese state or constitutes a favorable adaptation remains unclear, and the physiological and pathophysiological implications of the altered GH/IGF-I axis in obesity remain uncertain with GH neither being the cause nor the solution to reverse obesity

Risk was further elevated in male smokers taking more than 20 mg of B6 or 55 micrograms of B12 a day for 10 years

Carnitine deficiency seen in liver disease may cause metabolic dysfunctions in gluconeogenesis, fatty acid metabolism, albumin biosynthesis, and ammonia detoxification by the urea cycle [71]

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