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Would a traditional vaccine or viral-protein-nanoparticle vaccine that does not involve muscle cells be safer for FSHD patients before more research is done on the RNA-muscle vaccine

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To overcome the difficulties in targeting NRF2 for controlling NRF2-addicted cancers, targeting metabolic liabilities unique to NRF2-addicted cancer cells, such as dependency on exogenous NEAAs, including glutamine, is a very sensible way to achieve selective toxicity toward cancers that have fallen in NRF2 addiction

And each is designed to be used several times per week, with a new needle attached for each dose

10.1210/en.2016-1334 46 ElgamalR