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The POSITRON trial observed that sofosbuvir and RBV resulted in 78% overall SVR12, with 93% in HCV-2 and 61% in HCV-3 of patients for whom IFN treatment was not an option
However, it may fail to correctly identify 1a and 1b subtypes in a variable percentage of cases (514%) 15,16,17,18 , and tends to misclassify genotype 6 as genotype 1 16,23
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10.1016/j.arcmed.2008.06.005 124 PrataJ.MachadoA
