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BPC-157 supports this interconnected system by: Strengthening tight junctions between intestinal epithelial cells, reducing intestinal permeability (leaky gut) Modulating the enteric nervous system to normalize motility and reduce visceral hypersensitivity Regulating mucosal immune responses to prevent inappropriate inflammation against dietary and microbial antigens Conditions Treated with Oral BPC-157 Beyond Symptom Relief: Addressing Root Causes Unlike proton pump inhibitors (PPIs) that suppress stomach acid or corticosteroids that broadly dampen immunity, BPC-157 works by restoring the underlying structural and functional integrity of the gastrointestinal tract

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Nature cell biology 2013;15, 978990, doi: Kuilman, T

This is the first study to describe a rapid (within seconds) switch in NMDAR subunit composition triggered by neuronal activity

Psychological factors: Anxiety about injury, frustration with limitations, depression from activity restrictions all common and impactful