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Warchol, 2010)

Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance

Oxidative damage to lens proteins, particularly crystallins, leads to protein denaturation, aggregation, and cross-linking, reducing transparency

To overcome these events, we developed a strategy to protect the animals by treatment with atropine

While GLP-1 agonists may produce greater total weight loss, AOD-9604 more selectively targets fat tissue while preserving muscle mass

Both of these processes function in concert to reprogram metabolism in erythrocytes resulting in increased 2,3BPG synthesis