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The NOS family includes endothelial NOS (eNOS) and neuronal NOS (nNOS), both of which are constitutively expressed isoforms, as well as the transcriptionally regulated isoform, inducible NOS (iNOS), which has been shown to play an important role in host defense [1921]

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Those taking anticoagulants (particularly warfarin, requiring INR monitoring), antihypertensive medications (potential additive blood pressure lowering), or chemotherapy agents should also seek professional guidance due to potential interactions

Faecal microflora and -glucuronidase expression are altered in an irinotecan-induced diarrhea model in rats

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The viscosity is preferably lower than 500 cP, more preferably lower than 400 cP