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Alpha-methylacyl-CoA racemase (AMACR, also known as P504S or racemase) [35] is a commonly used cytoplasmic marker which is selective and very sensitive for carcinoma

Several mechanisms within the TME have been implicated in the resistance to anti-PD therapy, such as loss of neoantigens and low expression of PD-L1 [5]

doi:10.20945/2359-3997000000066

10.1136/jnnp-2019-322366 [DOI] [PMC free article] [PubMed] [Google Scholar] 18.Bossenmeyer-Pouri C, Smith AD, Lehmann S, Deramecourt V, Sablonnire B, Camadro JM, Pouri G, Kerek R, Helle D, Umoret R, Guant-Rodriguez RM, Rigau V, Gabelle A, Sequeira JM, Quadros EV, Daval JL, Guant J (2019) L., N-homocysteinylation of tau and MAP1 is increased in autopsy specimens of Alzheimers disease and vascular dementia

2019 Jan 1 [cited

This process is especially damaging in the context of chronic lung injury, where sustained epithelial death and release of DAMPs propagate inflammation and fibrotic remodeling