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As the surface characteristics are primarily responsible for the toxicity of the NPs, modification of surface chemistry and properties has been reported to be one of the most common devised strategies to mitigate NP toxicity (Figure 3) ( FIGURE 3 Surface coating is one of the most popular surface modification strategies to reduce the potential toxicity of NPs, which is reversible by non-covalent modification (Hwang et al., 2018)

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If this mutation takes place in critical region of an oncogene or tumor suppressor gene, it can lead to cancer

At 20mg/mL, those same 50 units deliver 10mg, double the intended dose

doi: 10.3389/fphar.2021.651926 71 de Marco CastroEMurphyCHRocheHM