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Under basal conditions, NRF2 is bound by Keap1 and targeted for degradation [57, 58]

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with activated phagocytes producing both reactive oxygen and nitrogen species

It's also worth noting that although Gln can be decomposed to Glu catalyzed by the glutaminases GLS1 and GLS2, only the catalysis of the latter is associated with ferroptosis (Gao et al

Immediately after washing, the cells were provided with a full cell culture medium and were placed in the incubator of the microscope (37C under a humidified 5% CO 2 atmosphere)