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83 , 84 and telomere shortening, which activates DNA damage responses leading to senescence 85 , 86 In the trabecular meshwork (TM), senescence impairs aqueous humor outflow due to extracellular matrix deposition and increased stiffness, elevating intraocular pressure and contributing to glaucoma

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10.1098/rstb.2014.0120 335 StewartJ.BachmanG.CooperC.LiuL.Ancoli-IsraelS.AlibiglouL

these are maturation disorders of red blood cells)