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Zihuai Recipe can improve ovarian reserve function in CTX-induced DOR rats

In the present study, increased p62 transcriptional levels observed in untreated azoospermia may indicate disrupted autophagy, possibly due to impaired lysosomal degradation, resulting in cellular waste accumulation and increased germ cell loss 43,44,45

Discussion In order to maintain energy and redox homeostasis under ischemia, the brain initiates intrinsic compensatory pathways, which among others comprise metabolic reprogramming strategies

HK3, in turn, impairs TAM cross-presentation capacity by promoting TFEB nuclear translocation and excessive lysosomal activation and antigen degradation, thereby undermining anti-tumor immunity

The ROS are also recognized for their signaling action in regulating developmental processes and in the development of stress tolerance (Mittler 2002

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