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J Mol Neurosci (2019) 67(1):6271

Bayerdorffer, M

Pechstein, et al

The bean will pop right out of the skin

In humans, local axonal disturbance leading to myokymia may be caused by demyelination (multiple sclerosis, Guillain-Barr syndrome, chronic inflammatory demyelinating polyneuropathy, radiation plexopathy), edema (pontine tumors), toxins (rattlesnake envenomation and clozapine administration), and ischemia, but not usually by nerve compression without the above changes

Another study found that IFN- downregulates melanin regulators (DCT, KITLG, FZD5), leading to decreased melanin production in melanocytes, and promotes lipid peroxidation (ROS) and ferroptosis in primary melanocytes derived from patients