liposomal vs injectable glutathione L-Glutathione: What's The Difference? The appeal of glutathione injections
Description
1999;71:S62S65
10.1016/j.pnpbp.2012.06.018 Prog Neuropsychopharmacol Biol Psychiatry
This is complicated because as a polar, charged tripeptide, transport of GSH is significantly inhibited by the blood-brain barrier (BBB), thus limiting effective delivery to brain-resident immune cells such as microglia which are central drivers of neuroinflammatory pathology (Valdovinos-Flores and Gonsebatt, 2012
GSH functions as a thiol buffer for many cellular proteins (metallothioneins, thioredoxins)
Similarly, Cheon et al
Ferroptosis promotes T-cell activation-induced neurodegeneration in multiple sclerosis
