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Lupus 11 , 501507 (2002)

Potential for desensitization with long-term use

GHK-Cu's anti-inflammatory effects flow through its broader gene-expression activity

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Ferroptosis susceptibility and impact on tumor growth differ between cancer types [204] and even within the same cancer type the protective ferroptotic pathway can change as shown for melanoma cells in which protection against ferroptosis shifts from GPX4 to FSP1 during lymphatic metastasis [205]