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Description
BJU Int 120 , 782792 (2017)

PMCID: PMC9869767

Mitochondrial ROS, a result of mitochondrial dysfunction, signals cellular stress and releases mitochondrial DNA (mtDNA), amplifying activation

PEA is thought to work by supporting the inflammatory response through the PPAR-a receptor, COX-2 and through effects on NF-kappaB signaling while also by restoring balance in the endocannabinoid system

Piepenburg et al., 2000)

FEBS J 273:31063117