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Tjong YW, Jian K, Li M, Chen M, Gao TM, Fung ML (2007) Elevated endogenous nitric oxide increases Ca 2+ flux via L-type Ca 2+ channels by S-nitrosylation in rat hippocampal neurons during severe hypoxia and in vitro ischemia

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This analysis indicates that gpx-1 (ortholog of human GPX4) RNAi leads to variable lifespan extension relative to wild-type controls and exhibits non-additive lifespan extension with fard-1(oe) (Figure 5figure supplement 1C)